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Traveling by bus from Lima to Cusco is a popular and scenic option for those eager to explore the rich culture and history of Peru, including the iconic Machu Picchu. The journey spans approximately 21 hours, covering about 1,100 kilometers (684 miles) through diverse landscapes, from arid coastal regions to the breathtaking Andean mountains.

Most travelers prefer to use reputable bus companies such as Cruz del Sur, Oltursa, or Movil Tours, which offer comfortable seats, onboard meals, and entertainment. It’s advisable to book your tickets in advance, especially during the high tourist season from June to August.

While on the bus, you'll be treated to stunning views as the landscape shifts from the Pacific coast to the highlands. Be sure to keep your camera handy, as you’ll pass through picturesque towns and rugged mountain passes. Don't forget to bring a jacket, as temperatures can drop significantly at night in the mountains.

For a taste of local culture, consider stopping at towns along the way, such as Abancay or Andahuaylas, where you can sample traditional Peruvian cuisine and experience the local lifestyle.

When you arrive in Cusco, take some time to acclimatize to the altitude, which is around 3,400 meters (11,200 feet) above sea level. Drink plenty of water and avoid strenuous activities for the first day.

From Cusco, the gateway to Machu Picchu, you can easily book a train or a guided tour to the ancient ruins. The bus ride is not just a means of transportation; it’s an integral part of your Peruvian adventure, offering a glimpse into the country’s stunning landscapes and rich cultural heritage.

In summary, taking the bus from Lima to Cusco is a rewarding experience that combines travel with cultural exploration, ultimately leading you to the awe-inspiring Machu Picchu.